Whinny’s Wisdoms

Springhill Equine Veterinary Clinic

Diagnosing and Treating Endocrine Disease in Horses

Greetings, fellow mice and equine enthusiasts, Whinny here! Gather ’round, for I have a tale to share about the remarkable value of diagnosing and treating endocrine diseases in our majestic equine friends. As a tiny mouse with a big voice, it’s my job to guide you through this adventure, where we’ll uncover the hidden treasures that lie within these medical marvels. So, grab your miniature saddle and join me as we embark on this journey of discovery! 

Unmasking the Hidden Villains: A Mouse’s Keen Eye!

In our quest to support the noble steeds, we must first unmask the hidden villains that plague their endocrine systems. With a keen eye for detail, our talented veterinary heroes employ diagnostic tools like hormone-level measurements and specialized blood tests that commonly include ACTH and insulin levels. These tools enable them to detect conditions such as equine metabolic syndrome (EMS) with insulin dysregulation, and pituitary pars intermedia dysfunction (PPID or Cushing’s disease). Like a mouse spotting a breadcrumb trail, their skills unravel the mysteries of these ailments, leading us to victory! Or at least a diagnosis.

As Endocrine Disorders are concerned, the two most common conditions that we are testing for are Equine Metabolic Syndrome (EMS) and Cushing’s Disease (PPID). EMS’s key feature is insulin dysregulation. Clinical signs for a horse with EMS can include laminitis, obesity, difficulty with weight loss, and regional adiposity (fat deposits in specific areas such as the crest, shoulder, and tailhead). On the other hand, Cushing’s Disease’s hallmark clinical sign is hypertrichosis, which is a fancy term for an excessively long and sometimes curly hair coat that does not shed out properly. Other signs can include chronic laminitis, loss of topline musculature, delayed healing and suspensory ligament breakdown.

Things can get tricky when a horse has both conditions at the same time. Reach out to your veterinarian if you think your horse is starting to show any of these clinical signs, as time is of the essence!

Tailored Treatment Options: A Mouse’s Secret Ingredient!

Armed with their vast knowledge, our veterinarians craft tailored treatment options to restore equine health. Each option is chosen to address the specific needs of the horse and their unique endocrine condition. Through the use of medications like pergolide for Cushing’s Disease and Insulin Wise or metformin for EMS, combined with lifestyle adjustments, we can bring balance back to our equine friends. As a tiny mouse, I’ve witnessed the transformation firsthand—these treatments are the secret ingredient that unlocks a world of wellness!

Springhill Equine Veterinary Clinic

Nutrition: Fueling Equine Resilience!

In our pursuit of equine resilience, nutrition takes center stage. Enter the wise nutrition gurus, who use their knowledge to create feeding programs. These programs often are tailored to control sugar and starch intake, incorporate forage and maintain ideal body condition. In the case of EMS, diet management is usually geared towards weight loss and limiting sugar and calories. This may include adding a grazing muzzle to limit grass intake and feeding a ration balancer instead of a complete or senior feed. On the other hand, Cushing’s Disease diet management is focused on current body condition score and whether or not the horse also has insulin dysregulation. Many Cushing’s patients with normal insulin levels graze on pasture and eat senior feeds. If they are overweight, or also have insulin dysregulation, then they will be on a ration balancer and restricted grass access.

Holistic Care: A Mouse’s Whisker of Extra Support!

While conventional treatments are essential, we must not overlook the holistic options. Acupuncture and herbal remedies can offer an extra dose of support on our equine heroes’ journey to wellness. These treatments, when integrated with veterinary care, help restore harmony and balance within their bodies. As a tiny mouse with a keen sense of curiosity, I’ve seen the sparkle return to their eyes and heard the spring in their hooves with the addition of acupuncture to their treatment plan.

Make sure you consult with my vets about any herbs, as they could contain something that conflicts with a medication they are on, or have the same base ingredient, and we don’t want to overload our horse’s system. Herbs may seem harmless, but many of our drugs are based on them, and the details are important!

Empowering the Equine Community: A Tiny Mouse’s Roar!

As we wrap up our adventure, let us not forget the value of empowering the equine community. Through knowledge sharing and raising awareness, we mice and horse lovers join forces to create a powerful alliance. By educating horse owners and caregivers about the signs of endocrine disorders, we empower them to take swift action and seek the support of our veterinary heroes. Together, we can roar like a mighty lion, ensuring the health and happiness of our cherished equine companions.


In this whimsical journey, we have discovered the value of diagnosing and treating endocrine diseases in horses. With a mouse’s keen eye, we can unmask the hidden villains, allowing our veterinary heroes to help our horse companions. Tailored treatment options, nutrition, and holistic care restore equilibrium to our equine friends’ lives. Through shared knowledge and a united alliance, we empower the horse and human bond.

Until next week,


P.S. Have you seen the latest Horse Girl Goes to the Vet video over on my YouTube Channel? It’s a riot! Just click on the blue text to watch it (it’s only 90 seconds!). Make sure you like and subscribe so you don’t miss out on upcoming material, like the First Aid for Horses series that’s coming out this fall!

Whinny’s Wisdoms is the official blog of Whinny the Clinic Mouse at Springhill Equine Veterinary Clinic in Newberry, Florida. If you liked this blog, please subscribe below, and share it with your friends on social media! For more information, please call us at (352) 472-1620, visit our website at SpringhillEquine.com, or follow us on Facebook!

[jetpack_subscription_form title="Subscribe to Whinny's Wisdoms"]

More Adventures of the Horse Doctor's Husband